Protein biomarker detection with unparalleled sensitivity, specificity, precision, and robustness

SPEAR UltraDetect™ biomarker assays employ a two-factor authenticated and homogeneous format to deliver best-in-class performance without the complexity of conventional wash-based workflows.

Patented SPEAR technology

Two-factor authentication ensures that the signal originates from genuine proximity binding, before amplification on standard qPCR.

Ultra-sensitive detection

By eliminating background and non-specific signal, SPEAR enables the detection of trace biomarkers in the single molecule range.

Ultra-small sample volume

Requires 100x less volume than other immunoassays - 1 µL or less of diluted sample.

One flexible platform, more biomarkers

Broadening the diversity of ultra-sensitive biomarker assays across a range of diseases.

Wash-free workflow

Homogeneous assay format with two-factor authentication enables ultra-sensitivity, without requiring high-affinity antibodies.

How can we help you?

Let’s discuss how SpearBio can accelerate your biomarker research and development.