How is the NAB-Sure™ SARS CoV-2 Assay different from other antibody tests?
NAB-Sure™ SARS-CoV-2 Assay is specific to neutralizing antibodies as opposed to total antibodies. Present ELISA and EIA immunoassays detect total antibodies against either SARS- CoV-2, the SARS-CoV-2 Spike Protein S1 subunit or the Receptor Binding Domain (RBD) on S1.
In addition, NAB-Sure™ SARS-CoV-2 Assay has many advantages over other neutralizing antibody tests. For example, cell-based assays take usually 3-4 days, have high inter-lab variations, and require Bio Safety Level (BSL) 2 – and above – laboratories due to the exposure risk using a live virus. ELISA-based surrogate virus neutralization assays have low sensitivity to detect antibodies from a small sample size.