What are neutralizing antibody assays for SARS-CoV-2?

Neutralizing antibody assays specifically detect antibodies that block SARS-CoV-2 virus from entering host cells. Existing methods to detect these antibodies include cell-based assays and ELISA-based surrogate virus neutralization assays. Cell-based assays include plaque reduction neutralization test (PRNT), microneutralization assay (MNA), and pseudotyped virus neutralization assay (PVA).

Posted Under: